Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109435 | 0.91 | LTA4H (0.75) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL640408 | 0.91 | CA4 (0.64) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL28222149 | 0.87 | CA4 (0.74) | CA4LTA4HPKMPGRHTT | |
| 1,4-Dimethoxybenzene SCHEMBL5960077 | 0.87 | CA1 (0.65) | CA4PKMCES2CES1CA1 | |
| SCHEMBL6291039 | 0.87 | BACE1 (0.59) | CA4LTA4HPKMHTTCA1 | |
| Anisole SCHEMBL22187427 | 0.87 | ALDH1A1 (0.67) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL4618570 | 0.85 | CA4 (0.70) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL27625071 | 0.85 | CA4 (0.70) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL1873043 | 0.85 | CA4 (0.70) | CA4LTA4HPKMPGRHTT | |
| Anisole SCHEMBL9876579 | 0.84 | CA4 (0.50) | CA4LTA4HPGRHTTNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283848-B | Novel coronavirus nsp16 inhibitor, preparation method thereof, virtual screening method and application | 中山大学 | 2024-12-10 | — | — | CN | claimed |
| CN-115925606-B | 5- (3- (sulfonamide) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof | 宁夏医科大学 | 2023-10-13 | — | — | CN | claimed |
| US-11773057-B2 | Naphthalenesulfonamide compound, preparation method, and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-10-03 | — | — | US | claimed |
| CN-116283848-A | Novel coronavirus nsp16 inhibitor, preparation method thereof, virtual screening method and application | 中山大学 | 2023-06-23 | — | — | CN | claimed |
| EP-3978471-B1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | UNIV CHINA PHARMA (CN) | 2023-02-22 | — | — | EP | claimed |
| US-20220251035-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2022-08-11 | — | — | US | claimed |
| CN-109897088-B | Phenylalanine derivative containing N- (2-oxoethyl) benzene sulfonamide and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | claimed |
| EP-3978471-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | China Pharmaceutical University (CN) | 2022-04-06 | — | — | EP | claimed |
| CN-109608369-B | Sulfonyl ester group anthraquinone derivative and preparation method and application thereof | 广西大学 | 2021-04-09 | — | — | CN | claimed |
| CN-112479945-A | Method for synthesizing beta-ketosulfone by one-pot method | 山东第一医科大学(山东省医学科学院) | 2021-03-12 | — | — | CN | claimed |
| CN-101497618-B | 4'-podophyllotoxin demethyl deoxidated aromatic ester, substituted benzene sulfonate, ether derivative and use in plant source pesticide preparation | UNIV NORTHWEST A&F | 2010-09-08 | — | — | CN | claimed |
| CN-101787136-A | Method for preparing polyurethane function material with surface modified by polyvinyl pyrrolidone | UNIV SOUTHEAST | 2010-07-28 | — | — | CN | claimed |
| CN-101781375-A | Preparation method of organic soluble photosensitive chitosan derivative | CHANGZHOU INST OF ADVANCED MAT | 2010-07-21 | — | — | CN | claimed |
| CN-101775084-A | Method for preparing organic-dissolvable photosensitive chitosan derivate | UNIV BEIJING CHEMICAL | 2010-07-14 | — | — | CN | claimed |
| CN-101497618-A | 4' -demethyl deoxypodophyllotoxin aromatic acid ester, substituted benzene sulfonate and ether derivative and application thereof in preparation of botanical pesticide | UNIV NORTHWEST A&F (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-101323597-A | Preparation of 4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amido) pyrimidine-5-formaldehyde | ANHUI QINGYUN PHARMACEUTICAL A (CN) | 2008-12-17 | — | — | CN | claimed |
| CN-101100461-A | Thiadiazole derivative for vulcanizing and crosslinking halogen-containing polymer and synthetic method thereof | PENGCHENG REN (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-101070295-A | Process for combined production of substituted benzenesulfonyl chloride and substituted benzoyl chloride | JIANGSU QINGSHENG CHEMICAL CO (CN) | 2007-11-14 | — | — | CN | claimed |
| CN-1308641-A | Polymerisation catalyst | BP CHEM INT LTD (GB) | 2001-08-15 | — | — | CN | claimed |
| CN-1249737-A | Method for acylation or sulphonation of aromatic compound | RHODIA CHIMIE SA (FR) | 2000-04-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773057-B2 | Naphthalenesulfonamide compound, preparation method, and application | NFE2L2, KEAP1, NFE2 | CA4 2200/4885LTA4H 401/4885PKM 532/4885 |
| US-20220251035-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | NFE2L2, KEAP1, NFE2 | CA4 2200/4885LTA4H 401/4885PKM 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.