Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409368 | 0.85 | TDP1 (0.52) | ALDH1A1NAMPTHTTKMT2AMEN1 | |
| SCHEMBL6410530 | 0.84 | MAPT (0.44) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL6403590 | 0.84 | ALDH1A1 (0.50) | EPHX2NR1H4ALDH1A1NAMPTKMT2A | |
| SCHEMBL6404074 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6403892 | 0.83 | LMNA (0.49) | EPHX2ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL6406614 | 0.83 | NAMPT (0.48) | EPHX2NAMPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6405551 | 0.83 | KMT2A (0.41) | EPHX2ALDH1A1NAMPTHTTKMT2A | |
| SCHEMBL6405202 | 0.83 | HSP90AA1 (0.47) | ALDH1A1NAMPTHTTKMT2AMEN1 | |
| SCHEMBL6407737 | 0.82 | HDAC6 (0.49) | ALDH1A1KMT2AMEN1TDP1GAA | |
| SCHEMBL6403585 | 0.82 | SMN1; SMN2 (0.55) | EPHX2NR1H4ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-6849717-B1 | Polycystic kidney disease gene homologs required for male mating behavior in nematodes and assays based thereon | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-02-01 | — | — | US | disclosed |
| US-6723557-B1 | PROVIDES A TOOL TO IDENTIFY THE GENES AND FACTORS INVOLVED IN THE POLYCYSTIC KIDNEY DISEASE PATHWAY, FOR DRUG SCREENING AND TREATMENT; LOCATION OF VULVA (LOV-1) GENE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | EPHX2 2961/4885NR1H4 3774/4885ALDH1A1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.