SCHEMBL640439

SCHEMBL640439

CC(C)Nc1nc(O)nc(O)n1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
HTT P42858 3/20 0.52
MAPK1 P28482 2/20 0.52
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
KMT2A Q03164 4/20 0.48
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 2/20 0.43
CYP1A2 P05177 1/20 0.43
KCNH3 Q9ULD8 2/20 0.42
MAPT P10636 1/20 0.37
CTSK P43235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2488992 0.95 GAA (0.58) GAATDP1HTTMAPK1F2
SCHEMBL3194672 0.84 KMT2A (0.46) GAATDP1HTTMAPK1F2
SCHEMBL637767 0.81 HTT (0.58) GAATDP1HTTMAPK1F2
SCHEMBL8041736 0.80 GAA (0.74) GAATDP1HTTMAPK1F2
SCHEMBL14163414 0.75 ALDH1A1 (0.47) GAATDP1HTTMAPK1F2
SCHEMBL4961492 0.75 GAA (0.48) GAATDP1HTTMAPK1F2
SCHEMBL8612319 0.75 MAPK1 (0.39) GAATDP1HTTMAPK1F2
SCHEMBL20117984 0.70 GAA (0.61) GAATDP1HTTMAPK1F2
SCHEMBL15599529 0.70 GAA (0.54) GAATDP1HTTMAPK1F2
SCHEMBL9970686 0.70 GAA (0.61) GAATDP1HTTMAPK1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11674162-B2 Selective advantage in fermentation GINKGO BIOWORKS, INC. (US) 2023-06-13 US claimed
US-20250076302-A1 DETECTING THE PRESENCE OF URINARY STONE DISEASE USING A PLURALITY OF URINARY METABOLITES THE CLEVELAND CLINIC FOUNDATION 2025-03-06 US disclosed
EP-4399293-A2 COMPOSITIONS COMPRISING A CAS12I POLYPEPTIDE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2024-07-17 EP disclosed
US-20230287456-A1 COMPOSITIONS COMPRISING A CAS12I POLYPEPTIDE AND USES THEREOF Arbor Biotechnologies, Inc. 2023-09-14 US disclosed
US-11674162-B2 Selective advantage in fermentation GINKGO BIOWORKS, INC. (US) 2023-06-13 US disclosed
WO-2023039534-A2 COMPOSITIONS COMPRISING A CAS12I POLYPEPTIDE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2023-03-16 WO disclosed
US-20220389465-A1 METHODS OF REDUCING BIURET IN UREA COMPOSITIONS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-12-08 US disclosed
WO-2021108667-A2 METHODS OF REDUCING BIURET IN UREA COMPOSITIONS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2021-06-03 WO disclosed
US-20210115430-A1 Immobilized Enzyme Complexes and Related Methods THE CURATORS OF THE UNIVERSITY OF MISSOURI 2021-04-22 US disclosed
EP-3625335-A1 IMMOBILIZED ENZYME COMPLEXES AND RELATED METHODS The Curators of the University of Missouri (US) 2020-03-25 EP disclosed
WO-2007107981-A9 METHODS, COMPOSITIONS AND DEVICES FOR MAINTAINING CHEMICAL BALANCE OF CHLORINATED WATER YEDA RES & DEV (IL) 2008-02-14 WO disclosed
WO-2007107981-A9 METHODS, COMPOSITIONS AND DEVICES FOR MAINTAINING CHEMICAL BALANCE OF CHLORINATED WATER YEDA RES & DEV (IL) 2008-02-14 WO disclosed
WO-2007107981-A2 METHODS, COMPOSITIONS AND DEVICES FOR MAINTAINING CHEMICAL BALANCE OF CHLORINATED WATER YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2007-09-27 WO disclosed
US-20050118665-A1 Methods for conducting assays for enzyme activity on protein microarrays PROTOMETRIX, INC. 2005-06-02 US disclosed
US-4745064-A Process for the degradation of s-triazine derivatives in aqueous solutions CIBA-GEIGY CORPORATION (US) 1988-05-17 US disclosed
EP-0141784-B1 PROCESS FOR THE DECOMPOSITION OF S-TRIAZINE DERIVATIVES IN AQUEOUS SOLUTIONS CIBA-GEIGY AG (CH) 1987-10-07 EP disclosed
EP-0141784-A1 Process for the decomposition of s-triazine derivatives in aqueous solutions CIBA-GEIGY AG (CH) 1985-05-15 EP disclosed
EP-0047719-B1 METHOD FOR THE DECOMPOSITION OF DERIVATIVES OF 2,4-DIHYDROXY-6-AMINO-S TRIAZINE CIBA-GEIGY AG (CH) 1984-11-28 EP disclosed
US-4415658-A EFFLUENTS CONTAINING HERBICIDE BY-PRODUCTS TREATED AEROBICALLY WITH PSEUDOMONAS CIBA-GEIGY CORPORATION (US) 1983-11-15 US disclosed
EP-0047719-A1 Method for the decomposition of derivatives of 2,4-dihydroxy-6-amino-s triazine CIBA-GEIGY AG (CH) 1982-03-17 EP disclosed