Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408678 | 0.80 | CYP3A4 (0.40) | CYP1A2CYP3A4CYP2C19POLBLMNA | |
| SCHEMBL6407620 | 0.79 | ALDH1A1 (0.48) | CYP1A2CYP2C19POLBKDM4EALDH1A1 | |
| SCHEMBL29340379 | 0.76 | TBXAS1 (0.50) | CYP1A2CYP3A4CYP2C19POLBLMNA | |
| SCHEMBL6411881 | 0.74 | SMN1; SMN2 (0.56) | CYP1A2CYP3A4CYP2C19POLBLMNA | |
| SCHEMBL6405361 | 0.72 | ALDH1A1 (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6408310 | 0.70 | KMT2A (0.52) | POLBLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL16907285 | 0.70 | BTK (0.49) | CYP1A2CYP3A4LMNAKDM4EALDH1A1 | |
| SCHEMBL10060497 | 0.70 | KMT2A (0.66) | POLBLMNAALDH1A1HPGDRXFP1 | |
| SCHEMBL13831073 | 0.70 | MAPT (0.65) | POLBALDH1A1HPGDRXFP1KMT2A | |
| SCHEMBL6411295 | 0.69 | MAPK14 (0.41) | CYP1A2CYP3A4LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | CYP1A2 93/4885CYP3A4 25/4885CYP2C19 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.