Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401372 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 | |
| SCHEMBL8315015 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 | |
| SCHEMBL27349990 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 | |
| SCHEMBL8239150 | 0.76 | PPARA (0.64) | ALDH1A1KMT2A | |
| SCHEMBL12305803 | 0.76 | PPARA (0.64) | ALDH1A1KMT2A | |
| SCHEMBL8305419 | 0.75 | PPARA (0.46) | ALDH1A1HTT | |
| SCHEMBL16879018 | 0.75 | LDHA (0.54) | ALDH1A1KMT2AMEN1POLBLDHA | |
| SCHEMBL16078668 | 0.75 | LDHA (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 | |
| SCHEMBL22444729 | 0.75 | LDHA (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 | |
| SCHEMBL20467759 | 0.75 | LDHA (0.54) | ALDH1A1KMT2AGLAF2RL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153408-A1 | 7-substituted-2-tetralone or bisulfite adduct is reduced microorganism (Candida) to optically active 7-substituted-2-tetralol;sulfonyl group is introduced to hydroxy group to form optically active 7-substituted-2-sulfonyloxytetralin; nitrogen substituent is introduced via ammonia; industrial scale | KANEKA CORPORATION (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1457570-A1 | PROCESS FOR PREPARATION OF 2-AMINOTETRALIN DERIVATIVES AND INTERMEDIATES THEREOF | KANEKA CORPORATION (JP) | 2004-09-15 | — | — | EP | disclosed |