SCHEMBL6405070

SCHEMBL6405070

O=C(O)c1cccc(Oc2c(-c3ccc(C(F)(F)F)c(C(F)(F)F)c3Oc3cccc(C(=O)O)c3C(=O)O)ccc(C(F)(F)F)c2C(F)(F)F)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.35
MAPK1 P28482 1/20 0.35
FABP4 P15090 1/20 0.34
RBP4 P02753 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
CLCN2 P51788 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
HPGD P15428 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406931 0.90 TAS2R14 (0.38) TAS2R14MAPK1FABP4RBP4MRGPRX4
SCHEMBL3193357 0.90 TAS2R14 (0.38) TAS2R14MAPK1FABP4RBP4MRGPRX4
SCHEMBL3744942 0.85 TAS2R14 (0.40) TAS2R14MAPK1FABP4RBP4MRGPRX4
SCHEMBL29962764 0.85 MAPK1 (0.41) TAS2R14MAPK1MRGPRX4CA12CA1
SCHEMBL29406692 0.84 MAPK1 (0.40) TAS2R14MAPK1MRGPRX4CA12CA1
SCHEMBL3194765 0.84 MAPK1 (0.40) TAS2R14MAPK1MRGPRX4CA12CA1
SCHEMBL3753479 0.81 TAS2R14 (0.41) TAS2R14MAPK1FABP4RBP4MRGPRX4
SCHEMBL29406934 0.80 CYP2C8 (0.41) FABP4MRGPRX4HPGDALDH1A1RXRA
SCHEMBL29963464 0.79 SCN8A (0.37) TAS2R14MAPK1FABP4MRGPRX4ALDH1A1
SCHEMBL28773737 0.79 FABP4 (0.44) TAS2R14FABP4RBP4MRGPRX4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 EP disclosed
WO-2014192665-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICOH COMPANY, LTD. (JP) 2014-12-04 WO disclosed
US-20120177425-A1 GLOSSY SURFACE FORMING APPARATUS AND GLOSSY SURFACE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-07-12 US disclosed
US-20050136245-A1 Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH COMPANY LIMITED (JP) 2005-06-23 US disclosed
US-5571579-A FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM HITACHI CHEMICAL COMPANY, LTD (JP) 1996-11-05 US disclosed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP disclosed
EP-0397153-B1 Chiral smectic liquid crystal device CANON KK (JP) 1995-08-02 EP disclosed
US-5426525-A Ferroelectric smectic liquid crystal device CANON KABUSHIKI KAISHA (JP) 1995-06-20 US disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed