SCHEMBL3744942

SCHEMBL3744942

O=C(O)c1cccc(Oc2c(-c3cccc(C(F)(F)F)c3Oc3cccc(C(=O)O)c3C(=O)O)cccc2C(F)(F)F)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.40
FABP4 P15090 1/20 0.39
MRGPRX4 Q96LA9 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
RBP4 P02753 2/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP1 P09874 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
DHODH Q02127 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28773737 0.92 FABP4 (0.44) TAS2R14FABP4MRGPRX4ALDH1A1HPGD
SCHEMBL3753479 0.90 TAS2R14 (0.41) TAS2R14FABP4MRGPRX4ALDH1A1HPGD
SCHEMBL6405070 0.85 TAS2R14 (0.35) TAS2R14FABP4MRGPRX4ALDH1A1HPGD
SCHEMBL3788013 0.85 TAS2R14 (0.38) TAS2R14FABP4MRGPRX4ALDH1A1HPGD
SCHEMBL29088055 0.84 MRGPRX4 (0.46) TAS2R14FABP4MRGPRX4ALDH1A1RBP4
SCHEMBL29962764 0.82 MAPK1 (0.41) TAS2R14MRGPRX4ALDH1A1HPGDMAPK1
SCHEMBL4858140 0.82 ALDH1A1 (0.39) TAS2R14FABP4MRGPRX4ALDH1A1HPGD
SCHEMBL29963464 0.82 SCN8A (0.37) TAS2R14FABP4MRGPRX4ALDH1A1MAPK1
SCHEMBL3194765 0.81 MAPK1 (0.40) TAS2R14MRGPRX4ALDH1A1HPGDMAPK1
SCHEMBL29962758 0.81 HTT (0.41) TAS2R14FABP4MRGPRX4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
EP-4446360-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-10-16 EP disclosed
WO-2024071066-A1 METAL-CLAD LAMINATED PLATE 日鉄ケミカル&マテリアル株式会社 2024-04-04 WO disclosed
WO-2023189319-A1 AMINO COMPOUND, POLYAMIDE ACID AND POLYIMIDE USING SAID AMINO COMPOUND, AND METHOD FOR PRODUCING SAME 日鉄ケミカル&マテリアル株式会社 2023-10-05 WO disclosed
WO-2023106369-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME 日鉄ケミカル&マテリアル株式会社 2023-06-15 WO disclosed
US-20210340325-A1 POLYIMIDE PRECURSOR, POLYIMIDE PRODUCED FROM SAME, AND FLEXIBLE DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-04 US disclosed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 EP disclosed
EP-0623830-A1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-11-09 EP disclosed
EP-0616234-A2 Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-09-21 EP disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
US-5108201-A From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-28 US disclosed
EP-0454590-A2 Polyimide optical waveguide NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-30 EP disclosed
US-4735492-A POLYIMIDE-ISOIDOLOQUINAZOLINEDIONE HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-04-05 US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed