Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | CDC25A | P30304 | 1/20 | 0.65 |
| ▸ | CDC25B | P30305 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887846 | 0.85 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1POLBMAPTCDC25A | |
| SCHEMBL30901621 | 0.84 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTTP53KMT2A | |
| SCHEMBL22019621 | 0.84 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1TP53SMN1; SMN2TSHR | |
| SCHEMBL6404890 | 0.82 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBMAPTCDC25A | |
| SCHEMBL17725688 | 0.81 | MEN1 (0.63) | ALDH1A1L3MBTL1MAPTTP53KMT2A | |
| SCHEMBL6404317 | 0.81 | ALDH1A1 (0.64) | ALDH1A1POLBMAPTCDC25ACDC25B | |
| SCHEMBL2496934 | 0.79 | NPC1 (0.73) | ALDH1A1L3MBTL1POLBMAPTCDC25A | |
| SCHEMBL21123650 | 0.79 | TP53 (0.78) | ALDH1A1L3MBTL1POLBMAPTTP53 | |
| SCHEMBL4147233 | 0.79 | CDC25A (1.00) | ALDH1A1L3MBTL1POLBMAPTCDC25A | |
| SCHEMBL19995460 | 0.77 | KMT2A (0.70) | ALDH1A1L3MBTL1POLBMAPTCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885L3MBTL1 2749/4885POLB 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.