Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534323 | 0.82 | NOS3 (0.41) | MAPKAPK2NOS3NOS2NOS1DHFR | |
| SCHEMBL28196797 | 0.82 | MAPKAPK2 (0.49) | MAPKAPK2NOS3NOS2DHFR | |
| SCHEMBL11223998 | 0.80 | MAPKAPK2 (0.38) | MAPKAPK2NOS3NOS2NOS1DHFR | |
| SCHEMBL91442 | 0.77 | MAPKAPK2 (0.37) | MAPKAPK2NOS3NOS2DHFR | |
| SCHEMBL25911875 | 0.77 | P2RX3 (0.36) | MAPKAPK2NOS3NOS2DHFR | |
| SCHEMBL31211307 | 0.77 | MAPKAPK2 (0.37) | MAPKAPK2NOS3NOS2DHFR | |
| SCHEMBL30852096 | 0.76 | MAPKAPK2 (0.33) | MAPKAPK2NOS3NOS2NOS1DHFR | |
| SCHEMBL18533485 | 0.76 | MAPKAPK2 (0.36) | MAPKAPK2NOS3NOS2NOS1DHFR | |
| SCHEMBL12020095 | 0.76 | MAPKAPK2 (0.36) | MAPKAPK2NOS3NOS2USP7 | |
| SCHEMBL3868054 | 0.74 | GABRP (0.41) | MAPKAPK2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6938484-B2 | Micromachined capacitive lateral accelerometer device and monolithic, three-axis accelerometer having same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-09-06 | — | — | US | disclosed |
| US-20040182155-A1 | Micromachined capacitive lateral accelerometer device and monolithic, three-axis accelerometer having same | MICHIGAN, UNIVERSITY OF THE REGENTS OF THE | 2004-09-23 | — | — | US | disclosed |
| WO-2004065968-A1 | MICROMACHINED CAPACITIVE LATERAL ACCELEROMETER DEVICE AND MONOLITHIC, THREE-AXIS ACCELEROMETER HAVING SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-08-05 | — | — | WO | disclosed |