SCHEMBL6405464

SCHEMBL6405464

O=C(O)[C@H]1CCCC[C@H]1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.59
MCL1 Q07820 1/20 0.53
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
RAB9A P51151 1/20 0.50
APEX1 P27695 1/20 0.50
GAA P10253 1/20 0.50
TAAR1 Q96RJ0 2/20 0.49
CYP2C19 P33261 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 2/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6405466 1.00 DGAT1 (0.59) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL6399371 1.00 DGAT1 (0.59) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL20370264 1.00 DGAT1 (0.59) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL3316742 1.00 DGAT1 (0.59) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL6399369 1.00 DGAT1 (0.59) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL8532640 0.96 DGAT1 (0.63) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL8532642 0.96 DGAT1 (0.63) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL15058791 0.96 DGAT1 (0.63) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL1252455 0.96 DGAT1 (0.63) DGAT1MCL1MAPTLMNARAB9A
SCHEMBL9920449 0.94 MCL1 (0.58) DGAT1MCL1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9869027-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-16 US disclosed
US-20160230289-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2016-08-11 US disclosed
US-9340759-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-17 US disclosed
US-20150136728-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-05-21 US disclosed
US-20050059658-A1 Pyridazinone BAYER AKTIENGESELLSCHAFT (DE) 2005-03-17 US disclosed
EP-1404657-A1 PYRIDAZINONE Bayer HealthCare AG (DE) 2004-04-07 EP disclosed
WO-2003002541-A1 PYRIDAZINONE BAYER HEALTHCARE AG (DE) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059658-A1 Pyridazinone TYMP, TPMT, PDXK DGAT1 4826/4885MCL1 2187/4885MAPT 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.