Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785633 | 1.00 | MAPT (0.63) | MAPTSMN1; SMN2POLBMAPK14RAB9A | |
| SCHEMBL169884 | 0.89 | MAPK14 (0.55) | MAPTSMN1; SMN2POLBMAPK14ALDH1A1 | |
| SCHEMBL15074691 | 0.86 | MAPK14 (0.53) | MAPTSMN1; SMN2POLBMAPK14ALDH1A1 | |
| SCHEMBL21605079 | 0.86 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2POLBMAPK14RAB9A | |
| SCHEMBL30147800 | 0.86 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2POLBMAPK14RAB9A | |
| SCHEMBL10202322 | 0.84 | ALDH1A1 (0.52) | MAPTSMN1; SMN2POLBMAPK14ALDH1A1 | |
| SCHEMBL2605840 | 0.83 | ALDH1A1 (0.50) | MAPTSMN1; SMN2MAPK14ALDH1A1KDM4E | |
| SCHEMBL2296326 | 0.83 | MAPT (0.68) | MAPTSMN1; SMN2POLBMAPK14RAB9A | |
| SCHEMBL30713111 | 0.82 | MAPT (0.56) | MAPTSMN1; SMN2POLBRAB9AMEN1 | |
| SCHEMBL27171644 | 0.82 | MAPT (0.56) | MAPTSMN1; SMN2POLBRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240316017-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | LG CHEM, LTD. (KR) | 2024-09-26 | — | — | US | disclosed |
| US-20240300944-A1 | NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR | LG CHEM, LTD. (KR) | 2024-09-12 | — | — | US | disclosed |
| EP-4349826-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | LG Chem, Ltd. (KR) | 2024-04-10 | — | — | EP | disclosed |
| EP-4339197-A1 | NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR | Lg Chem, Ltd. (KR) | 2024-03-20 | — | — | EP | disclosed |
| CN-117500805-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |
| US-20050020564-A1 | Pyrazole-amides and sulfonamides as sodium channel modulators | ABBOTT LABORATORIES | 2005-01-27 | — | — | US | disclosed |
| US-20040220170-A1 | Pyrazole-amides and sulfonamides as sodium channel modulators | ABBOTT LABORATORIES | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240316017-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | RET, ROS1, MST1R | MAPT 4155/4885SMN1; SMN2 4287/4885POLB 4598/4885 |
| US-20240300944-A1 | NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR | CDKN1A, RET, UBTF | MAPT 2721/4885SMN1; SMN2 4350/4885POLB 3957/4885 |
| US-20050020564-A1 | Pyrazole-amides and sulfonamides as sodium channel modulators | SCN3A, KCNN3, TRPV3 | MAPT 4316/4885SMN1; SMN2 395/4885POLB 4785/4885 |
| US-20040220170-A1 | Pyrazole-amides and sulfonamides as sodium channel modulators | SCN3A, KCNN3, TRPV3 | MAPT 4316/4885SMN1; SMN2 395/4885POLB 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.