SCHEMBL64055

SCHEMBL64055

CO[SiH](OC)c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ACHE P22303 2/20 0.43
ALDH1A1 P00352 4/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA7 P43166 3/20 0.35
CA9 Q16790 3/20 0.35
ESR1 P03372 1/20 0.34
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 2/20 0.32
CYP1A2 P05177 2/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30492014 1.00 TSHR (0.43) TSHRACHEALDH1A1CA1CA2
SCHEMBL1659040 0.87 TSHR (0.36) TSHRACHEALDH1A1CA1CA2
SCHEMBL9148449 0.84 CA1 (0.38) TSHRACHEALDH1A1CA1CA2
SCHEMBL17391479 0.83 TSHR (0.33) TSHRACHE
SCHEMBL17391507 0.83 CA4 (0.38) TSHRACHECA4
SCHEMBL27101093 0.83 TSHR (0.30) TSHRACHE
SCHEMBL2293342 0.81 TRPA1 (0.39) TSHRACHEALDH1A1CA1CA2
SCHEMBL27595314 0.78 TSHR (0.41) TSHRACHEALDH1A1CA1CA2
SCHEMBL28931541 0.78 ALDH1A1 (0.52) TSHRACHEALDH1A1CA1CA2
SCHEMBL17391482 0.78 ALDH1A1 (0.30) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3883 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037202-A Silicone resin modified waterproof material, preparation method and application thereof 宁波润禾高新材料科技股份有限公司 2026-05-15 CN claimed
US-20250353967-A1 CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-20 US claimed
EP-4634324-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2025-10-22 EP claimed
EP-4636012-A1 OPTICAL ARTICLE COMPRISING A HIGH REFRACTIVE INDEX ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO ENVIRONMENTAL CONDITIONS Essilor International (FR) 2025-10-22 EP claimed
CN-120136483-A Preparation method and application of modified naphthalene water reducer 浙江五龙新材股份有限公司 2025-06-13 CN claimed
CN-120082330-A Medium-temperature phase-change microcapsule material and preparation method thereof 中国石油化工股份有限公司 2025-06-03 CN claimed
CN-120024900-A Nano silicon carbide microsphere and preparation method and application thereof 苏州纳微先进微球材料应用技术研究所有限公司 2025-05-23 CN claimed
CN-120005060-A Functional prepolymerized catalyst component for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-116478405-B Silane oligomer and preparation method and application thereof 万华化学集团股份有限公司 2025-05-13 CN claimed
CN-116693728-B Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2025-05-06 CN claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed
EP-0147053-B1 A CATALYST AND A PROCESS FOR POLYMERIZATION OF OLEFINS Tonen Corporation (JP) 1990-09-05 EP claimed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US claimed
EP-0145368-B1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMERS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-03-08 EP claimed
EP-0191543-A1 Silicone insect toxicants VENTEC LABORATORIES, INC. (US) 1986-08-20 EP claimed
US-4560711-A Transparent organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1985-12-24 US claimed
US-4500600-A GAMMAAMINOPROPYLTRIMETHOXYSILANE AND ANOTHER ALKOXYSILANE OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-02-19 US claimed
US-4179537-A ALKOXYSILANES, SUBSTITUTED ALKOXYSILANES RYKOWSKI JOHN J 1979-12-18 US claimed
US-4030813-A Control element having liquid layer attainable to geometrically uneven state in response to electrical signal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-06-21 US claimed
US-3959242-A MOLD RELEASE SURFACE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US claimed