Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408473 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1ALOX15ATMHSD17B10CTSB | |
| SCHEMBL6403885 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1ALOX15ATMHSD17B10CTSB | |
| SCHEMBL6405499 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ALOX15ATMHSD17B10CTSB | |
| SCHEMBL6408244 | 0.75 | POLB (0.60) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL6407138 | 0.75 | RAB9A (0.46) | ALDH1A1CTSBSMN1; SMN2TP53HPGD | |
| SCHEMBL5484015 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CTSBSMN1; SMN2HPGDMEN1 | |
| SCHEMBL6408107 | 0.73 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL13462071 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1ALOX15ATMHSD17B10SMN1; SMN2 | |
| SCHEMBL515046 | 0.69 | ALDH1A1 (0.49) | ALDH1A1ALOX15ATMHSD17B10CTSB | |
| SCHEMBL9693032 | 0.69 | HPGD (0.57) | ALDH1A1CTSBSMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885ALOX15 2151/4885ATM 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.