Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408473 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6407138 | 0.78 | RAB9A (0.46) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6404879 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TP53MEN1HPGD | |
| SCHEMBL6406930 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6015609 | 0.75 | RAB9A (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6405499 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6405373 | 0.73 | GSK3A (0.50) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6408940 | 0.72 | NPC1 (0.58) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6408555 | 0.71 | CYP2D6 (0.45) | SMN1; SMN2ALDH1A1TP53CTSBMEN1 | |
| SCHEMBL6407548 | 0.70 | CYP2C9 (0.52) | ALDH1A1RAB9AMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | SMN1; SMN2 4793/4885ALDH1A1 720/4885TP53 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.