Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12110672 | 0.85 | OXTR (0.69) | MEN1KMT2AMAPK1ALDH1A1HPGD | |
| SCHEMBL10035357 | 0.84 | OXTR (0.64) | MEN1KMT2AMAPK1ALDH1A1G6PD | |
| SCHEMBL11919913 | 0.83 | OXTR (0.52) | ALDH1A1OXTRMAPTGLAHSD17B10 | |
| SCHEMBL10432252 | 0.83 | ALDH1A1 (0.55) | MEN1KMT2AMAPK1ALDH1A1HPGD | |
| SCHEMBL10012186 | 0.83 | OXTR (0.61) | MEN1KMT2AALDH1A1HPGDOXTR | |
| SCHEMBL10035350 | 0.82 | OXTR (0.69) | MEN1KMT2AMAPK1ALDH1A1G6PD | |
| SCHEMBL10035326 | 0.82 | OXTR (0.69) | MEN1KMT2AMAPK1ALDH1A1G6PD | |
| SCHEMBL6402514 | 0.79 | OXTR (0.57) | MEN1KMT2AALDH1A1HPGDOXTR | |
| SCHEMBL1104405 | 0.79 | OXTR (0.65) | MEN1KMT2AMAPK1ALDH1A1HPGD | |
| SCHEMBL20514201 | 0.79 | APLNR (0.73) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | MEN1 3562/4885KMT2A 2263/4885MAPK1 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.