Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407564 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1L3MBTL1MEN1MMP1 | |
| SCHEMBL6409341 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1L3MBTL1MEN1MMP1 | |
| SCHEMBL6409345 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1L3MBTL1MEN1MMP1 | |
| SCHEMBL6408141 | 0.81 | POLB (0.56) | ALDH1A1L3MBTL1NOTUMPOLBSMN1; SMN2 | |
| SCHEMBL23451628 | 0.79 | POLB (0.75) | ALDH1A1L3MBTL1NOTUMPOLBSMN1; SMN2 | |
| SCHEMBL31686338 | 0.79 | NOTUM (0.58) | ALDH1A1L3MBTL1MMP2NOTUMPOLB | |
| SCHEMBL6404107 | 0.78 | SMN1; SMN2 (0.53) | KMT2AALDH1A1L3MBTL1MEN1MMP1 | |
| SCHEMBL6404106 | 0.78 | SMN1; SMN2 (0.53) | KMT2AALDH1A1L3MBTL1MEN1MMP1 | |
| SCHEMBL31124145 | 0.75 | NOTUM (0.54) | ALDH1A1L3MBTL1MMP2NOTUMPOLB | |
| SCHEMBL6409331 | 0.75 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1NOTUMPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | KMT2A 986/4885ALDH1A1 1486/4885L3MBTL1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.