Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409341 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL6404107 | 0.84 | SMN1; SMN2 (0.53) | KMT2AMEN1L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL6404106 | 0.84 | SMN1; SMN2 (0.53) | KMT2AMEN1L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL6407560 | 0.81 | KMT2A (0.57) | KMT2AMEN1L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL6407564 | 0.81 | KMT2A (0.57) | KMT2AMEN1L3MBTL1ALDH1A1MMP1 | |
| SCHEMBL6407737 | 0.78 | HDAC6 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6404146 | 0.77 | EPHX2 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6409950 | 0.76 | RAB9A (0.50) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6407803 | 0.76 | RAB9A (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6408033 | 0.74 | NPC1 (0.52) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | KMT2A 986/4885MEN1 3154/4885L3MBTL1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.