Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408837 | 0.88 | HSPA5 (0.47) | HSPA5MEN1KMT2AACLYGRIK1 | |
| SCHEMBL6410292 | 0.88 | HSPA5 (0.62) | HSPA5STK39ALDH1A1CYP3A4TSHR | |
| SCHEMBL6407663 | 0.86 | NPC1 (0.50) | HSPA5STK39ALDH1A1MEN1KMT2A | |
| SCHEMBL6411984 | 0.82 | HSPA5 (0.47) | HSPA5STK39MEN1KMT2AMAPK1 | |
| SCHEMBL6408135 | 0.81 | KCNMA1 (0.55) | HSPA5TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6414621 | 0.80 | HSPA5 (0.48) | HSPA5STK39ALDH1A1CYP3A4TSHR | |
| SCHEMBL6407492 | 0.79 | CXCR2 (0.47) | HSPA5STK39ALDH1A1MEN1KMT2A | |
| SCHEMBL6407982 | 0.79 | HSPA5 (0.44) | HSPA5STK39ALDH1A1CYP3A4MEN1 | |
| SCHEMBL6409629 | 0.78 | KDM5A (0.47) | HSPA5GPR35STK39ALDH1A1TSHR | |
| SCHEMBL4356208 | 0.76 | TRPV1 (0.60) | ALDH1A1MEN1KMT2AMAPK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | claimed |
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | HSPA5 4261/4885HSP90AA1 3508/4885GPR35 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.