Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405896 | 0.80 | SMN1; SMN2 (0.69) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6402396 | 0.79 | SMN1; SMN2 (0.77) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6402577 | 0.78 | SMN1; SMN2 (0.72) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6402991 | 0.77 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6405972 | 0.77 | ALDH1A1 (0.65) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6403524 | 0.77 | KMT2A (0.68) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6407762 | 0.75 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6407606 | 0.75 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6404207 | 0.75 | KMT2A (0.59) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6404219 | 0.74 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | NPC1 1915/4885RAB9A 4044/4885SMN1; SMN2 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.