Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341603 | 0.93 | ALDH1A1 (0.43) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL6168133 | 0.90 | ALDH1A1 (0.41) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13387618 | 0.89 | MAPT (0.47) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL6169282 | 0.83 | ALDH1A1 (0.52) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13387757 | 0.81 | MAPT (0.47) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13388217 | 0.81 | ALDH1A1 (0.43) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL6340205 | 0.81 | BRD4 (0.44) | ALDH1A1MEN1KMT2ALMNAPTGER4 | |
| SCHEMBL13387655 | 0.80 | ALDH1A1 (0.48) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13387585 | 0.79 | LMNA (0.42) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13387493 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239808-A1 | Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur | TRANSMIT GESELLSCHAFT FUR TECHNOLOGIETRANSFER MBH (DE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239808-A1 | Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur | PRNP, APP, MAPT | ALDH1A1 1606/4885POLB 3592/4885HTT 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.