Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409336 | 0.82 | NOTUM (0.55) | MAPTNPC1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL6408613 | 0.81 | NOTUM (0.55) | MAPTNPC1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL6434804 | 0.80 | CA12 (0.44) | NPC1SMN1; SMN2RAB9AHTTMEN1 | |
| SCHEMBL6403916 | 0.78 | NPC1 (0.50) | NPC1SMN1; SMN2RAB9AHTTMEN1 | |
| SCHEMBL6409980 | 0.78 | RAB9A (0.48) | MAPTNPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6404913 | 0.78 | ALDH1A1 (0.43) | MAPTNPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL6402371 | 0.77 | CA12 (0.45) | NPC1SMN1; SMN2RAB9AMEN1HPGD | |
| SCHEMBL1313860 | 0.75 | CYP1A2 (0.61) | CHRNB2CHRNA4MAPTNPC1SMN1; SMN2 | |
| SCHEMBL6402481 | 0.75 | HPGD (0.59) | MAPTNPC1SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL6409269 | 0.73 | S1PR3 (0.48) | NPC1SMN1; SMN2RAB9AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | CHRNB2 2280/4885CHRNA4 1983/4885MAPT 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.