Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930093 | 0.84 | ESR1 (0.48) | PRKCZMDM2ALDH1A1MEN1LMNA | |
| SCHEMBL10480393 | 0.83 | OPRD1 (0.51) | MDM2OPRD1ALDH1A1NOTUMTSHR | |
| SCHEMBL5332712 | 0.82 | AVPR1A (0.51) | MDM2OPRD1ALDH1A1MEN1KMT2A | |
| SCHEMBL1104410 | 0.78 | MDM2 (0.46) | MDM2ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL14293441 | 0.78 | GUSB (0.43) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL1104429 | 0.76 | GLA (0.56) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL14345465 | 0.75 | ALDH1A1 (0.48) | MDM2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11511067 | 0.73 | AVPR1A (0.59) | OPRD1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29713827 | 0.72 | OPRD1 (0.53) | OPRD1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10012472 | 0.72 | MEN1 (0.41) | ALDH1A1MEN1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PRKCZ 2400/4885MDM2 1609/4885OPRD1 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.