Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.77 |
| ▸ | PGR | P06401 | 7/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777800 | 0.92 | NR3C1 (0.67) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL6405034 | 0.89 | NR3C1 (0.78) | NR3C1PGRNR3C2 | |
| SCHEMBL3650510 | 0.87 | NR3C1 (1.00) | NR3C1PGRNR3C2 | |
| SCHEMBL4826339 | 0.86 | NR3C1 (0.84) | NR3C1PGRNR3C2 | |
| SCHEMBL3650890 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2 | |
| SCHEMBL3651746 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2 | |
| SCHEMBL4822471 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL4822119 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2 | |
| SCHEMBL3652499 | 0.84 | NR3C1 (0.81) | NR3C1PGRNR3C2 | |
| SCHEMBL14269098 | 0.84 | NR3C1 (1.00) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | IL1B, NFKBIA, BBOX1 | NR3C1 1483/4885PGR 3289/4885NR3C2 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.