Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410890 | 0.88 | CFTR (0.45) | EGFRKDRMEN1KMT2AHPGD | |
| SCHEMBL6410337 | 0.72 | ALDH1A1 (0.44) | EGFRKDRMEN1KMT2AHPGD | |
| SCHEMBL6408208 | 0.70 | ALDH1A1 (0.43) | EGFRKDRMEN1KMT2AHPGD | |
| SCHEMBL6412162 | 0.66 | TEK (0.56) | KDRMEN1KMT2AHPGDGSK3B | |
| SCHEMBL30628468 | 0.64 | TSHR (0.50) | MEN1KMT2AHPGDRAB9AMAPT | |
| SCHEMBL1277058 | 0.64 | TSHR (0.50) | MEN1KMT2AHPGDRAB9AMAPT | |
| SCHEMBL15077970 | 0.64 | RAF1 (0.80) | RAF1BRAFEGFRRETKIF5B | |
| SCHEMBL6433669 | 0.64 | CFTR (0.43) | EGFRMEN1KMT2AKDM4ETHRB | |
| SCHEMBL6432626 | 0.62 | EGFR (0.42) | EGFRKDRGSK3BRAB9A | |
| SCHEMBL6408590 | 0.62 | TEK (0.41) | EGFRKDRMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |