Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408208 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDKMT2AUBE2N | |
| SCHEMBL6412162 | 0.85 | TEK (0.56) | ALDH1A1KDM4EHPGDKMT2AUBE2N | |
| SCHEMBL6408590 | 0.81 | TEK (0.41) | ALDH1A1KDM4EHPGDKMT2AUBE2N | |
| SCHEMBL6433669 | 0.75 | CFTR (0.43) | KDM4EKMT2AMEN1CFTRTP53 | |
| SCHEMBL439175 | 0.74 | NOTUM (0.46) | ALDH1A1KDM4EHPGDKMT2AUBE2N | |
| SCHEMBL6410303 | 0.74 | MAPT (0.33) | ALDH1A1KDM4EHPGDKMT2ANPSR1 | |
| SCHEMBL6432626 | 0.73 | EGFR (0.42) | KDRGSK3BEGFR | |
| SCHEMBL6410890 | 0.73 | CFTR (0.45) | ALDH1A1KDM4EHPGDKMT2AUBE2N | |
| SCHEMBL6408652 | 0.72 | RAF1 (0.43) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL1786166 | 0.71 | TEK (0.71) | ALDH1A1KDM4EHPGDKMT2AUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |