Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410337 | 0.75 | ALDH1A1 (0.44) | CFTREGFRTP53MEN1KMT2A | |
| SCHEMBL6432626 | 0.71 | EGFR (0.42) | AURKAEGFRCD38 | |
| SCHEMBL21141404 | 0.65 | TNK2 (0.51) | AURKAEGFRMEN1KMT2ACHEK1 | |
| SCHEMBL6408208 | 0.65 | ALDH1A1 (0.43) | AURKAEGFRMEN1KMT2AGFER | |
| SCHEMBL14013960 | 0.64 | TNK2 (0.70) | AURKAEGFRTHRBMEN1KMT2A | |
| SCHEMBL6408652 | 0.64 | RAF1 (0.43) | CFTREGFRTHRBMEN1KMT2A | |
| SCHEMBL5319683 | 0.64 | KDR (0.78) | KDM4EL3MBTL1 | |
| SCHEMBL29850051 | 0.63 | NPC1 (0.60) | EGFRMEN1KMT2AMAPK10GFER | |
| SCHEMBL21258999 | 0.63 | NPC1 (0.60) | EGFRMEN1KMT2AMAPK10GFER | |
| SCHEMBL21141395 | 0.60 | TNK2 (0.43) | AURKAEGFRTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |