Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163894 | 0.94 | CYP1A2 (0.55) | USP30F10CTSBCTSSCTSK | |
| SCHEMBL6411254 | 0.89 | USP30 (0.57) | USP30F10CTSBCTSSCTSK | |
| SCHEMBL5161097 | 0.89 | USP30 (0.57) | USP30F10CTSBCTSSCTSK | |
| SCHEMBL6407354 | 0.83 | NPC1 (0.57) | USP30CTSBCTSSCTSKL3MBTL1 | |
| Bentiromide SCHEMBL151634 | 0.83 | CTSL (0.62) | USP30CTSSCTSKL3MBTL1CYP1A2 | |
| Bentiromide SCHEMBL3250992 | 0.83 | CTSL (0.62) | USP30CTSSCTSKL3MBTL1CYP1A2 | |
| Bentiromide SCHEMBL1001794 | 0.83 | CTSL (0.62) | USP30CTSSCTSKL3MBTL1CYP1A2 | |
| SCHEMBL2899982 | 0.83 | HDAC8 (0.61) | USP30CTSBCTSSCTSKL3MBTL1 | |
| SCHEMBL2899984 | 0.83 | HDAC8 (0.61) | USP30CTSBCTSSCTSKL3MBTL1 | |
| SCHEMBL7275364 | 0.83 | CA2 (0.62) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277690-A1 | Small molecules for treatment of hypercholesterolemia and related diseases | AVANIR PHARMACEUTICALS | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277690-A1 | Small molecules for treatment of hypercholesterolemia and related diseases | LDLR, NPC1L1, CETP | USP30 3092/4885F10 3001/4885CTSB 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.