Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404261 | 0.88 | TDP1 (0.50) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6405222 | 0.87 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6403020 | 0.87 | NPC1 (0.52) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6403892 | 0.85 | LMNA (0.49) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6406019 | 0.85 | KMT2A (0.55) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6408035 | 0.85 | KMT2A (0.51) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6403173 | 0.85 | NPC1 (0.46) | RAB9ASMN1; SMN2SLC5A7NPC1MAPT | |
| SCHEMBL6402555 | 0.82 | HPGD (0.55) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6404311 | 0.81 | NPC1 (0.55) | RAB9ASMN1; SMN2SLC5A7NPC1MEN1 | |
| SCHEMBL6403819 | 0.79 | TDP1 (0.52) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | RAB9A 4044/4885SMN1; SMN2 4458/4885SLC5A7 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.