Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404261 | 0.87 | TDP1 (0.50) | NPC1RAB9ASMN1; SMN2SLC5A7POLB | |
| SCHEMBL6403020 | 0.86 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2SLC5A7POLB | |
| SCHEMBL6405222 | 0.86 | SMN1; SMN2 (0.59) | NPC1RAB9AEPHX2PPARGSMN1; SMN2 | |
| SCHEMBL6409358 | 0.85 | RAB9A (0.53) | NPC1RAB9AEPHX2SMN1; SMN2SLC5A7 | |
| SCHEMBL6407783 | 0.84 | MLYCD (0.45) | EPHX2SMN1; SMN2HDAC4LSSMLYCD | |
| SCHEMBL6408035 | 0.84 | KMT2A (0.51) | NPC1RAB9AEPHX2PPARGSMN1; SMN2 | |
| SCHEMBL6402555 | 0.81 | HPGD (0.55) | NPC1RAB9AEPHX2SMN1; SMN2HDAC4 | |
| SCHEMBL6404311 | 0.81 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HDAC4SLC5A7 | |
| SCHEMBL18031837 | 0.77 | POLB (0.50) | NPC1RAB9AEPHX2SMN1; SMN2POLB | |
| SCHEMBL6407566 | 0.77 | RAB9A (0.46) | NPC1RAB9AEPHX2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | NPC1 1915/4885RAB9A 4044/4885PPARA 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.