Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414599 | 0.91 | KMT2A (0.54) | ALDH1A1KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL5751986 | 0.81 | MEN1 (0.61) | ALDH1A1TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6411963 | 0.81 | KMT2A (0.61) | ALDH1A1L3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL13257660 | 0.79 | ALDH1A1 (0.77) | ALDH1A1KDM4EL3MBTL1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL6415511 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL6416291 | 0.76 | TSHR (0.50) | ALDH1A1KDM4ETSHRLMNAKMT2A | |
| SCHEMBL6260057 | 0.76 | KMT2A (0.54) | ALDH1A1KDM4EL3MBTL1LMNAKMT2A | |
| SCHEMBL6264113 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL6503020 | 0.75 | GPBAR1 (0.58) | ALDH1A1KDM4EL3MBTL1LMNAKMT2A | |
| SCHEMBL6265709 | 0.75 | KMT2A (0.59) | ALDH1A1KDM4EL3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | AVENTIS PHARMA (FR) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | TUBB3, TUBB, TUBB1 | ALDH1A1 1270/4885KDM4E 3143/4885L3MBTL1 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.