SCHEMBL9799896

SCHEMBL9799896

CCC(=O)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
TDP1 Q9NUW8 4/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 3/20 0.52
TSHR P16473 3/20 0.51
HPGD P15428 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MEN1 O00255 1/20 0.49
ALOX15 P16050 1/20 0.49
MAPK1 P28482 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678635 1.00 L3MBTL1 (0.55) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL7072347 0.89 TTR (0.52) L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1
SCHEMBL15546827 0.87 ALOX15 (0.58) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL2708161 0.86 CYP1A2 (0.56) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL8580243 0.86 CHRM1 (0.57) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL11343615 0.86 ALDH1A1 (0.50) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL9595497 0.85 TDP1 (0.56) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL645781 0.85 TDP1 (0.56) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL28921963 0.85 CYP1A2 (0.54) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT
SCHEMBL8332048 0.84 FFAR1 (0.57) L3MBTL1SMN1; SMN2TDP1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-B1 OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE CIBA-GEIGY AG (CH) 1985-07-24 EP disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed