Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DHPS | P49366 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800297 | 0.87 | NR3C1 (0.48) | CLK4DHPSNR3C1PGRTRPV1 | |
| SCHEMBL6405434 | 0.84 | NR3C1 (0.52) | DHPSNR3C1PGRTRPV1NPC1 | |
| SCHEMBL4732615 | 0.84 | NR3C1 (0.44) | CLK4DHPSNR3C1PGRTRPV1 | |
| SCHEMBL4630288 | 0.84 | NR3C1 (0.49) | NR3C1PGRTRPV1 | |
| SCHEMBL5777869 | 0.84 | NR3C1 (0.56) | NR3C1PGR | |
| SCHEMBL5796840 | 0.83 | NR3C1 (0.55) | DHPSNR3C1PGRTRPV1 | |
| SCHEMBL6411423 | 0.83 | NR3C1 (0.46) | DHPSNR3C1PGRTRPV1 | |
| SCHEMBL4732633 | 0.82 | NR3C1 (0.57) | NR3C1PGRTRPV1NPC1LMNA | |
| SCHEMBL6403528 | 0.82 | NR3C1 (0.63) | DHPSNR3C1PGRTRPV1NPC1 | |
| SCHEMBL5777174 | 0.82 | NR3C1 (0.45) | DHPSNR3C1PGRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090559-A1 | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | IL1B, NFKBIA, BBOX1 | CLK4 2434/4885DHPS 198/4885NR3C1 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.