Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407336 | 0.84 | EPHX1 (0.63) | ALDH1A1HPGDNPC1RAB9AGAA | |
| SCHEMBL6405950 | 0.83 | NPC1 (0.55) | ALDH1A1HPGDUSP2NPC1RAB9A | |
| SCHEMBL6408604 | 0.82 | EPHX1 (0.61) | ALDH1A1HPGDNPC1RAB9AGAA | |
| SCHEMBL6410506 | 0.81 | HPGD (0.46) | ALDH1A1HPGDUSP2NPC1RAB9A | |
| SCHEMBL19263070 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDUSP2SMN1; SMN2LMNA | |
| SCHEMBL6404220 | 0.79 | KMT2A (0.50) | ALDH1A1NPC1RAB9AERCC1ERCC4 | |
| SCHEMBL507837 | 0.77 | ALDH1A1 (0.90) | ALDH1A1HPGDUSP2ALOX12NPC1 | |
| SCHEMBL6401607 | 0.77 | EPHX2 (0.57) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18829414 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HPGDUSP2ALOX12ERCC1 | |
| SCHEMBL6244724 | 0.76 | ALDH1A1 (0.93) | ALDH1A1HPGDUSP2ALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | ALDH1A1 1486/4885HPGD 3244/4885USP2 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.