Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403203 | 0.82 | EPHX2 (0.61) | EPHX2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6410506 | 0.79 | HPGD (0.46) | EPHX2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL6409920 | 0.77 | ALDH1A1 (0.59) | EPHX2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6404231 | 0.76 | POLB (0.52) | EPHX2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15470638 | 0.74 | EPHX2 (0.56) | EPHX2ALDH1A1LMNASLC5A7NPC1 | |
| SCHEMBL19263071 | 0.74 | LMNA (0.41) | EPHX2LMNAMEN1KMT2ARAB9A | |
| SCHEMBL6407634 | 0.74 | POLB (0.53) | EPHX2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL19263024 | 0.74 | EPHX2 (0.60) | EPHX2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL19263070 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL19263069 | 0.72 | POLB (0.51) | EPHX2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | EPHX2 2961/4885ALDH1A1 1486/4885LMNA 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.