Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179116 | 0.82 | KDM4E (0.59) | KDM4EMAPTMAPK1ALDH1A1PKM | |
| SCHEMBL10480044 | 0.81 | KDM4E (0.67) | KDM4EMAPTMAPK1ALDH1A1PKM | |
| SCHEMBL7675644 | 0.80 | LTB4R (0.60) | ALDH1A1NPC1HPGD | |
| SCHEMBL6236449 | 0.78 | CA12 (0.47) | MAPTALDH1A1HSD17B10POLBCA12 | |
| SCHEMBL17187944 | 0.77 | KDM4E (0.42) | KDM4EPOLBGLA | |
| SCHEMBL9579625 | 0.76 | KDM4E (0.59) | KDM4EMAPTMAPK1ALDH1A1PKM | |
| SCHEMBL4360840 | 0.76 | KDM4E (0.73) | KDM4EMAPTMAPK1ALDH1A1PKM | |
| SCHEMBL5713415 | 0.75 | PPARA (0.36) | ALDH1A1HSD17B10CFDPOLB | |
| SCHEMBL17187947 | 0.75 | GABRP (0.35) | KDM4EHPSE | |
| SCHEMBL10828174 | 0.73 | KDM4E (0.56) | KDM4EMAPTMAPK1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562951-A2 | PORPHYRIN DERIVATIVES | Photobiotics Ltd. (GB) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046151-A2 | PORPHYRIN DERIVATIVES | PHOTOBIOTICS LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |