Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172806 | 0.98 | NAAA (0.55) | NAAAHTTAPPDGKAGAA | |
| SCHEMBL10172836 | 0.92 | NAAA (0.59) | NAAAHTTAPPDGKAGAA | |
| Propionic Acid SCHEMBL27519317 | 0.85 | NAAA (0.56) | NAAAHTTDGKARAD52NPSR1 | |
| SCHEMBL13331043 | 0.85 | NAAA (0.48) | NAAAHTTAPPDGKAGAA | |
| SCHEMBL28245871 | 0.83 | NAAA (0.47) | NAAAHTTAPPDGKAGAA | |
| SCHEMBL28517022 | 0.82 | DGKA (0.47) | NAAAAPPDGKAALDH1A1RAD52 | |
| SCHEMBL4353576 | 0.81 | APP (0.41) | NAAAAPPDGKAGAACA2 | |
| SCHEMBL16693727 | 0.81 | DGKA (0.55) | NAAADGKAALDH1A1RAD52NPSR1 | |
| SCHEMBL20008841 | 0.80 | NAAA (0.53) | NAAAHTTDGKAGAAALDH1A1 | |
| SCHEMBL16316349 | 0.79 | NAAA (0.41) | NAAAHTTGAARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708765-B1 | BIOCOMPATIBLE POLYMERIZATION ACCELERATORS | SURMODICS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-8202833-B2 | Coating of polymer containing N-vinyl groups on cells, tissue | SURMODICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20050112086-A1 | Biocompatible polymerization accelerators | SURMODICS, INC. | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050112086-A1 | Biocompatible polymerization accelerators | VCL, PCNA, CD38 | NAAA 716/4885HTT 2657/4885APP 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.