SCHEMBL28517022

SCHEMBL28517022

CCCC(=O)OCCCS(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.47
NAAA Q02083 1/20 0.42
HTR2C P28335 1/20 0.42
ALDH1A1 P00352 2/20 0.41
DNM1 Q05193 1/20 0.40
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA1A P35348 1/20 0.36
FAAH O00519 1/20 0.36
APP P05067 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
ATM Q13315 1/20 0.35
PAM P19021 2/20 0.35
TLR2 O60603 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17753939 0.94 NAAA (0.46) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL16693727 0.91 DGKA (0.55) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL17753911 0.88 DGKA (0.45) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL11329487 0.87 DGKA (0.67) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL11345638 0.87 DGKA (0.67) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL11344752 0.87 DGKA (0.67) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL11336270 0.87 DGKA (0.67) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL10946414 0.86 DGKA (0.65) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL10948667 0.86 DGKA (0.65) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL10945189 0.86 DGKA (0.65) DGKANAAAHTR2CALDH1A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115157-A1 FORMULATIONS CONTAINING ACETAMINOPHEN AND SULFOALKYL ETHER CYCLODEXTRIN CYDEX PHARMACEUTICALS INC (US) 2026-04-30 US disclosed
US-12527755-B2 Formulations containing acetaminophen and sulfoalkyl ether cyclodextrin CYDEX PHARMACEUTICALS, INC. (US) 2026-01-20 US disclosed
US-20240358544-A1 METHOD OF TREATING VISION LOSS IN A HUMAN SUBJECT WITH PHOTOREACTIVE COMPOUNDS KIORA PHARMACEUTICALS PTY LTD (AU) 2024-10-31 US disclosed
US-20230357451-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2023-11-09 US disclosed
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2023-10-24 US disclosed
EP-3183295-B1 FRACTIONATED ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2023-08-02 EP disclosed
US-20230002513-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2023-01-05 US disclosed
EP-4083075-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CyDex Pharmaceuticals, Inc. (US) 2022-11-02 EP disclosed
US-20220332853-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2022-10-20 US disclosed
CN-112239466-B Succinate salt of a selective CDK4/6 inhibitor and crystalline forms thereof 常州千红生化制药股份有限公司 2021-06-08 CN disclosed
CN-112239466-A Succinate salt of a selective CDK4/6 inhibitor and crystalline forms thereof 常州千红生化制药股份有限公司 2021-01-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358544-A1 METHOD OF TREATING VISION LOSS IN A HUMAN SUBJECT WITH PHOTOREACTIVE COMPOUNDS PDE6C, ALDH1A2, PDE6D DGKA 3306/4885NAAA 1990/4885HTR2C 1554/4885
US-20260115157-A1 FORMULATIONS CONTAINING ACETAMINOPHEN AND SULFOALKYL ETHER CYCLODEXTRIN CYP2C8, CYP3A43, SULT2A1 DGKA 4708/4885NAAA 2512/4885HTR2C 1460/4885
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same AGPS, DDOST, ALG1 DGKA 599/4885NAAA 3265/4885HTR2C 4682/4885
US-12527755-B2 Formulations containing acetaminophen and sulfoalkyl ether cyclodextrin TPMT, GSTP1, ALB DGKA 4811/4885NAAA 4043/4885HTR2C 730/4885
US-20220332853-A1 MANUFACTURING PROCESS FOR CYCLODEXTRIN DERIVATIVES DCXR, AGL, OSTC DGKA 1608/4885NAAA 4419/4885HTR2C 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.