Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917643 | 0.81 | LMNA (0.51) | LMNAMAPK1MCOLN3KMT2AMAPT | |
| SCHEMBL14484846 | 0.77 | L3MBTL1 (0.66) | LMNAKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL14696990 | 0.75 | LMNA (0.75) | LMNAMAPK1KMT2AMAPTALDH1A1 | |
| SCHEMBL5143836 | 0.75 | ALDH1A1 (0.63) | LMNAMCOLN3KMT2AMAPTNPC1 | |
| SCHEMBL10259764 | 0.74 | LMNA (0.61) | LMNAMCOLN3MAPTALDH1A1HSD17B10 | |
| SCHEMBL1003299 | 0.73 | MAPK1 (0.79) | LMNAMAPK1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19916764 | 0.73 | MAPK1 (0.79) | LMNAMAPK1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL18617342 | 0.73 | ALDH1A1 (0.64) | LMNAMCOLN3KMT2AMAPTALDH1A1 | |
| SCHEMBL10293140 | 0.73 | LMNA (0.61) | LMNAKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL1001348 | 0.72 | ALDH1A1 (0.66) | LMNAKMT2AMAPTNPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |