Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410659 | 0.89 | FNTA (0.33) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL6469829 | 0.86 | FNTA (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL6416690 | 0.85 | FNTA (0.34) | FNTAFNTBPGGT1BP2RX7 | |
| SCHEMBL6448742 | 0.82 | FNTA (0.37) | FNTAFNTBPGGT1B | |
| SCHEMBL6413197 | 0.81 | FPR1 (0.32) | FNTAFNTBPGGT1B | |
| SCHEMBL7532834 | 0.81 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7653568 | 0.80 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL7161934 | 0.78 | FNTA (0.55) | FNTAFNTBPGGT1B | |
| SCHEMBL6416078 | 0.78 | FNTA (0.36) | FNTAFNTBPGGT1B | |
| SCHEMBL7166984 | 0.77 | PRMT5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090012-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1090012-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000001702-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |