SCHEMBL6410799

SCHEMBL6410799

COC(=O)C1C(C)C1COC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.43
SLC6A1 P30531 2/20 0.43
KIF11 P52732 4/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
KMT2A Q03164 1/20 0.39
SLC6A12 P48065 1/20 0.39
SLC6A13 Q9NSD5 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TYMP P19971 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
ALOX15 P16050 1/20 0.37
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481384 1.00 SLC6A11 (0.43) SLC6A11SLC6A1KIF11SMN1; SMN2MEN1
SCHEMBL6407666 0.95 SMN1; SMN2 (0.43) SLC6A11SLC6A1SMN1; SMN2MEN1TP53
SCHEMBL6414832 0.92 POLB (0.41) SLC6A1KIF11MEN1TP53CYP1A2
SCHEMBL6406022 0.90 SLC6A11 (0.47) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL6415874 0.90 SLC6A11 (0.47) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL6406931 0.90 SLC6A11 (0.41) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL6408185 0.90 SLC6A11 (0.41) SLC6A11SLC6A1KIF11MEN1TP53
SCHEMBL6406914 0.90 SLC6A11 (0.41) SLC6A11SLC6A1KIF11SMN1; SMN2MEN1
SCHEMBL6408753 0.86 SLC6A11 (0.45) SLC6A11SLC6A1MEN1TP53CYP1A2
SCHEMBL6407574 0.85 SLC6A11 (0.45) SLC6A11SLC6A1MEN1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 SLC6A11 2935/4885SLC6A1 2874/4885KIF11 3259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.