Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043959 | 0.90 | ACACB (0.38) | ACACBALDH1A1MAPTLMNAHNF4A | |
| SCHEMBL5047191 | 0.89 | LMNA (0.38) | ACACBALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL6409602 | 0.87 | LMNA (0.34) | PARP10ALDH1A1MAPTMAPK1SIRT2 | |
| SCHEMBL5050668 | 0.87 | HNF4A (0.35) | PARP10ACACBHNF4A | |
| SCHEMBL5049705 | 0.86 | PARP10 (0.44) | PARP10ALDH1A1MAPTMAPK1SIRT2 | |
| SCHEMBL5047199 | 0.84 | BRD4 (0.35) | ACACBALDH1A1MAPTMAPK1SIRT2 | |
| SCHEMBL5048419 | 0.83 | ACACB (0.37) | ACACBLMNA | |
| SCHEMBL5047239 | 0.83 | ACACB (0.37) | ACACBALDH1A1MAPT | |
| SCHEMBL5050793 | 0.83 | BRD4 (0.37) | ACACBMAPTLMNABRD4 | |
| SCHEMBL5049731 | 0.83 | HDAC1 (0.37) | HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513803-A1 | LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS | Galderma Research & Development, S.N.C. (FR) | 2005-03-16 | — | — | EP | claimed |
| WO-2003101945-A1 | LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2003-12-11 | — | — | WO | claimed |