Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 18/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309128 | 0.91 | PDE2A (0.40) | PDE2AALDH1A1SPR | |
| SCHEMBL310170 | 0.91 | HTT (0.39) | PDE2AALDH1A1SPR | |
| SCHEMBL6416356 | 0.91 | HDAC3 (0.39) | PDE2AALDH1A1SPR | |
| SCHEMBL309774 | 0.91 | HDAC3 (0.41) | PDE2APDE10AALDH1A1SPR | |
| SCHEMBL310204 | 0.88 | CCR6 (0.46) | ALDH1A1SPR | |
| SCHEMBL3770851 | 0.86 | SPR (0.43) | ALDH1A1SPR | |
| SCHEMBL309552 | 0.86 | SPR (0.43) | ALDH1A1SPR | |
| SCHEMBL309343 | 0.86 | SPR (0.43) | ALDH1A1SPR | |
| SCHEMBL309075 | 0.86 | SPR (0.53) | PDE2APDE10AALDH1A1SPR | |
| SCHEMBL10042205 | 0.85 | TSHR (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313413-B1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES | CONVERGENCE PHARMACEUTICALS (GB) | 2012-05-16 | — | — | EP | disclosed |