Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641983 | 0.86 | GAA (0.66) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5073382 | 0.84 | GAA (0.52) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL640994 | 0.84 | ACHE (0.51) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL642234 | 0.83 | GAA (0.62) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL642341 | 0.82 | ACHE (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL642893 | 0.82 | ALDH1A1 (0.62) | GAAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9965441 | 0.82 | SMN1; SMN2 (0.48) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9965439 | 0.81 | KMT2A (0.53) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9965398 | 0.81 | SMN1; SMN2 (0.50) | GAAPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL640909 | 0.81 | SLC6A4 (0.48) | CHRM1HTR1ASLC6A2SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11571433-B2 | Methods for treating memory impairment and cognitive dysfunction | CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD. (IL) | 2023-02-07 | — | — | US | claimed |
| CN-114404425-A | Inhibitor of phosphodiesterase and application thereof | 南京中医药大学 | 2022-04-29 | — | — | CN | claimed |
| CN-114395011-A | Preparation method of natural bufogenin lactone compounds | 上海中医药大学 | 2022-04-26 | — | — | CN | claimed |
| US-20210085693-A1 | METHODS FOR TREATING MEMORY IMPAIRMENT AND COGNITIVE DYSFUNCTION | CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD. (IL) | 2021-03-25 | — | — | US | claimed |
| EP-3755340-A1 | METHODS FOR TREATING MEMORY IMPAIRMENT AND COGNITIVE DYSFUNCTION | Carmel-Haifa University Economic Corporation Ltd. (IL) | 2020-12-30 | — | — | EP | claimed |
| WO-2019162945-A1 | METHODS FOR TREATING MEMORY IMPAIRMENT AND COGNITIVE DYSFUNCTION | CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD. (IL) | 2019-08-29 | — | — | WO | claimed |
| CN-104034834-B | The detection method of bufanolide dienes ingredients fingerprint and application thereof in a kind of dried venom of toads medicinal material | HEHUANG PHARMACEUTICAL CO., LTD., SHANGHAI (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-104034834-A | Method for detecting fingerprints of toad bufanolide diene compositions in toad medicinal materials and application of method | SHANGHAI HUTCHISON PHARMACEUTICALS CO LTD | 2014-09-10 | — | — | CN | claimed |
| CN-103599112-A | Application of bufanolide diene compound in preparation of medicines for treating sepsis immune paralysis | NANJING UNIVERSITY OF TECHNOLOGY | 2014-02-26 | — | — | CN | claimed |
| CN-1985851-B | Lipoid microsphere injection containing toad cake extract and its preparing method | SHENYANG YAODA MEDICINE DEV CO LTD | 2012-01-25 | — | — | CN | claimed |
| CN-1985851-A | Lipoid microsphere injection containing toad cake extract and its preparing method | SHENYANG YAODA MEDICINE DEV CO (CN) | 2007-06-27 | — | — | CN | claimed |
| WO-2006120472-A2 | NOVEL BETA-STEROID COMPOUNDS | GUY'S AND ST THOMAS'NHS FOUNDATION TRUST (GB) | 2006-11-16 | — | — | WO | claimed |
| EP-4619039-A1 | METHODS AND COMPOSITIONS INCLUDING CONJUGATED DNAZYMES | 1E Therapeutics, Ltd. (IL) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105654-A1 | METHODS AND COMPOSITIONS INCLUDING CONJUGATED DNAZYMES | 1E THERAPEUTICS, LTD. (IL) | 2024-05-23 | — | — | WO | disclosed |
| US-20230265424-A1 | METHODS OF TREATING AND PREVENTING BACTERIAL INFECTIONS | 1E THERAPEUTICS LTD. (IL) | 2023-08-24 | — | — | US | disclosed |
| EP-3394080-B1 | LIPID-LINKED PRODRUGS | UNIV BRITISH COLUMBIA (CA) | 2023-06-07 | — | — | EP | disclosed |
| US-5932613-A | PINE ROOT FUNGAL METABOLITE OR ANALOG | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5917084-A | PINE ROOT (DEUTERO MYCETES) FUNGAL METABOLITE, NATURALLY OCCURRING TERPENOID COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| WO-1998000091-A2 | ANTIFUNGAL AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| WO-1998000121-A1 | ANTICANCER AGENTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265424-A1 | METHODS OF TREATING AND PREVENTING BACTERIAL INFECTIONS | DNASE1, UNG, DNASE1L3 | GAA 82/4885PKM 3265/4885KMT2A 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.