SCHEMBL6412433

SCHEMBL6412433

COc1ccc(C(OCC2CC2C(=O)O)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 7/20 0.47
SLC6A1 P30531 3/20 0.47
FFAR4 Q5NUL3 6/20 0.47
SLC6A12 P48065 2/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 1/20 0.47
SLC6A13 Q9NSD5 1/20 0.47
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6409688 0.97 SLC6A11 (0.51) SLC6A11SLC6A1FFAR4SLC6A12MEN1
SCHEMBL6414906 0.97 SLC6A11 (0.51) SLC6A11SLC6A1FFAR4SLC6A12MEN1
SCHEMBL6407696 0.88 SLC6A11 (0.42) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL6406106 0.87 SLC6A11 (0.47) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL6407715 0.87 SLC6A11 (0.47) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL6406390 0.85 FFAR4 (0.49) SLC6A1FFAR4MEN1KMT2ACA1
SCHEMBL27057181 0.85 FFAR4 (0.49) SLC6A1FFAR4MEN1KMT2ACA1
SCHEMBL6407591 0.84 CA1 (0.47) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL6532658 0.84 SLC6A11 (0.40) SLC6A11SLC6A1SLC6A12MEN1TP53
SCHEMBL6407580 0.84 CA1 (0.45) SLC6A11SLC6A1SLC6A12MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 SLC6A11 2935/4885SLC6A1 2874/4885FFAR4 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.