SCHEMBL6412480

SCHEMBL6412480

CCOC(=O)C1CC1COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.45
CA2 P00918 10/20 0.45
CA9 Q16790 8/20 0.45
CA12 O43570 7/20 0.45
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
MDM2 Q00987 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27057179 1.00 CA1 (0.45) CA1CA2CA9CA12MAPT
SCHEMBL1140016 0.92 CA1 (0.39) CA1CA2CA9CA12MAPT
SCHEMBL6407580 0.92 CA1 (0.45) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL6412784 0.92 CA1 (0.45) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL6407591 0.87 CA1 (0.47) CA1CA2CA9CA12TSHR
SCHEMBL1139618 0.86 MEN1 (0.36) CA1CA2CA9CA12MAPT
SCHEMBL6415837 0.86 CYP1A2 (0.44) MAPTTSHRSMN1; SMN2
SCHEMBL6447636 0.85 CA1 (0.45) CA1CA2CA9CA12MAPT
SCHEMBL1139941 0.85 MAPT (0.37) CA1CA2CA9CA12MAPT
SCHEMBL6407546 0.83 CYP2C19 (0.38) CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
WO-2023244788-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2023-12-21 WO disclosed
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 CA1 143/4885CA2 379/4885CA9 655/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 CA1 4843/4885CA2 4086/4885CA9 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.