SCHEMBL6407546

SCHEMBL6407546

CC(C)(C)OC(=O)C1CC1COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
SLC6A1 P30531 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
KIF11 P52732 1/20 0.35
FFAR4 Q5NUL3 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ABCB1 P08183 1/20 0.34
ELANE P08246 1/20 0.34
KCNA3 P22001 1/20 0.34
KDM1A O60341 1/20 0.33
MAOB P27338 1/20 0.33
GPR119 Q8TDV5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6412728 0.92 SLC6A11 (0.44) SLC6A1KMT2AMEN1KIF11
SCHEMBL6414764 0.92 SLC6A11 (0.44) SLC6A1KMT2AMEN1KIF11
SCHEMBL6532658 0.87 SLC6A11 (0.40) SLC6A1KMT2AMEN1L3MBTL1
SCHEMBL6415837 0.86 CYP1A2 (0.44) CYP2C19KMT2AMEN1
SCHEMBL6447900 0.85 CYP2C19 (0.36) CYP2C19HIF1AKMT2AFFAR4CA12
SCHEMBL6412480 0.83 CA1 (0.45) CA12CA1
SCHEMBL27057179 0.83 CA1 (0.45) CA12CA1
SCHEMBL27057181 0.82 FFAR4 (0.49) SLC6A1KMT2AMEN1KIF11FFAR4
SCHEMBL6406390 0.82 FFAR4 (0.49) SLC6A1KMT2AMEN1KIF11FFAR4
SCHEMBL31473972 0.80 KIF11 (0.42) CYP2C19SLC6A1KMT2AMEN1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 CYP2C19 160/4885HIF1A 949/4885SLC6A1 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.