Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439473 | 0.87 | SLC6A4 (0.53) | DRD3SLC6A4KCNH2BCHENPC1 | |
| SCHEMBL6449429 | 0.77 | SLC6A4 (0.48) | SLC6A4KCNH2BCHENPC1RAB9A | |
| SCHEMBL6411523 | 0.74 | SLC6A4 (0.67) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL6454014 | 0.73 | SLC6A4 (0.65) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL6418906 | 0.72 | SLC6A4 (0.53) | SLC6A4KCNH2BCHENPC1RAB9A | |
| SCHEMBL4570310 | 0.71 | HRH3 (0.66) | HRH3DRD3NPC1RAB9AKDM4E | |
| SCHEMBL11694424 | 0.70 | HRH3 (0.56) | HRH3DRD3KDM4EMAPTHTT | |
| SCHEMBL16606233 | 0.69 | HRH3 (0.60) | HRH3DRD3NPC1KDM4EMAPT | |
| SCHEMBL27691343 | 0.69 | HRH3 (0.64) | HRH3DRD3NPC1RAB9AKDM4E | |
| SCHEMBL16606225 | 0.68 | HRH3 (0.59) | HRH3DRD3NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | HRH3 61/4885DRD3 28/4885SLC6A4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.