Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431531 | 0.85 | SLC6A4 (0.58) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL4634065 | 0.85 | SLC6A4 (0.58) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL6431527 | 0.85 | SLC6A4 (0.58) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL6410766 | 0.85 | SLC6A4 (0.48) | SLC6A4KCNH2NPC1RAB9ASLC6A2 | |
| SCHEMBL6414218 | 0.84 | CHRM2 (0.47) | SLC6A4KCNH2UBE2MDCUN1D1DRD4 | |
| SCHEMBL4634827 | 0.83 | C5AR1 (0.43) | UBE2MDCUN1D1 | |
| SCHEMBL6415646 | 0.81 | ALDH1A1 (0.40) | SLC6A4KCNH2SLC6A2SLC6A3MCHR1 | |
| SCHEMBL4634432 | 0.74 | SLC6A4 (0.76) | SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL6412856 | 0.74 | SLC6A4 (0.76) | SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL6439473 | 0.74 | SLC6A4 (0.53) | SLC6A4KCNH2NPC1RAB9ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | SLC6A4 1/4885KCNH2 754/4885NPC1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.