Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | AGER | Q15109 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431531 | 0.85 | SLC6A4 (0.58) | DRD4SLC6A4KCNH2 | |
| SCHEMBL4634065 | 0.85 | SLC6A4 (0.58) | DRD4SLC6A4KCNH2 | |
| SCHEMBL6431527 | 0.85 | SLC6A4 (0.58) | DRD4SLC6A4KCNH2 | |
| SCHEMBL6418906 | 0.84 | SLC6A4 (0.53) | DRD4UBE2MDCUN1D1SLC6A4KCNH2 | |
| SCHEMBL6410766 | 0.83 | SLC6A4 (0.48) | DRD4UBE2MDCUN1D1SLC6A4KCNH2 | |
| SCHEMBL25090900 | 0.78 | MEN1 (0.46) | CHRM2CHRM3OPRM1HSD11B1UBE2M | |
| SCHEMBL24424433 | 0.78 | MEN1 (0.46) | CHRM2CHRM3OPRM1HSD11B1UBE2M | |
| SCHEMBL4635081 | 0.75 | PDK2 (0.45) | CHRM2CHRM3AGERKCNH2 | |
| SCHEMBL4635628 | 0.72 | CHRM2 (0.68) | CHRM2CHRM3DRD4OPRM1SLC6A12 | |
| SCHEMBL4634737 | 0.72 | CHRM2 (0.68) | CHRM2CHRM3DRD4OPRM1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | CHRM2 178/4885CHRM3 219/4885DRD4 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.