Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | GRN | P28799 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498910 | 0.84 | ALDH1A1 (1.00) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL6415839 | 0.84 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL19994231 | 0.80 | ALDH1A1 (0.74) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL1259093 | 0.74 | ALDH1A1 (0.66) | ALDH1A1GAAGRNSORT1MAPK1 | |
| SCHEMBL6261953 | 0.74 | KMT2A (0.48) | ALDH1A1GAAMAPK1LMNAKMT2A | |
| SCHEMBL13912473 | 0.73 | ALDH1A1 (0.77) | ALDH1A1GAAGRNSORT1SMN1; SMN2 | |
| SCHEMBL5402973 | 0.73 | ALDH1A1 (0.63) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL68764 | 0.73 | RPA1 (0.65) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL4422536 | 0.72 | ALDH1A1 (0.75) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL2927650 | 0.71 | ALDH1A1 (0.74) | ALDH1A1GAAGRNSORT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | ALDH1A1 360/4885GAA 1397/4885GRN 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.